Looking to move to Carlsbad and want to connect with local employers? Fill out this form and we’ll help you get recruited.
Benefits: Bonus based on performance Free uniforms Health insurance Training & development Benefits/Perks: Competitive Pay Professional Development Job Stability in a growing industry Hourly + Commission Growth opportunity Job Description The Personal Lines Producer at Pay Low Insurance is responsible for maintaining and maximizing profitable relationships with personal lines clients and for growing the book of business through new client sales. Responsibilities: Identify, qualify, and develop personal insurance opportunities with new and existing clients in person, online, by phone, and through written communication. Foster and maintain excellent relationships with clients and prospects through regular follow-up, accurate and timely quotations, and general account support. Anticipate, respond to, and follow up on all existing client needs. Actively prospect round accounts, and solicit increases in existing client coverage as well as network for new clients, including win backs. Obtain best coverage/rate for insured, process quotes, and bind insurance coverage; follow up as necessary with inspection, photos, and other documentation. Present policies to insured and educate them on coverages and rates. Foster and maintain excellent relationships with customers and prospects through regular follow-up, timely quotations, and general account support. Support and prepare clients for renewal and retention, and maintain strong client relationships. Anticipate, respond to, and follow up on all existing client needs. Monitor, review, and report on key metrics to ensure sales targets are achieved and execute sales activity documentation in a timely, accurate, and professional manner. Collaborate with team members, mentor staff, provide expertise and answer questions, and participate in formal and informal meetings as needed. Maintain CE and participate in ongoing education and keep informed regarding industry information, new product information, legislation, coverages, and technology to continuously improve knowledge and performance. Qualifications: Possess a valid driver’s license and a source of reliable transportation. Demonstrate strong knowledge of insurance products and usages, rating procedures, underwriting procedures, coverages, and industry operations to effectively secure new business and maintain an existing client base. Have a proven track record of business-to-business sales success. Possess strong presentation, persuasion, and negotiation skills with the ability to close sales. Be people-oriented, customer-focused, and professionally assertive in developing new client relationships and servicing existing clients. Possess outstanding organizational skills with an ability to complete difficult assignments without supervision, sound business judgment, strong decision-making, and superior written and verbal communication skills. Have excellent time management skills, thrive in a team environment, and Technology and Computer proficiency including agency management systems.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! RESEARCH ASSOCIATE II, ANALYTICAL DEVELOPMENT & QUALITY CONTROL (ADQC) SUMMARY: Seeking an experienced analytical chemist to join our Analytical Development & Quality Control (ADQC) group at the Research Associate II level. The ideal candidate will be familiar with HPLC and other chemistry techniques, possess a strong work ethic and strong technical background, demonstrate excellent oral and written communication skills, and have experience working in a GMP environment. The successful candidate will be able to perform the following responsibilities with a high degree of independence and attention to detail. RESPONSIBILITIES: Conduct routine and non-routine analysis of Raw and Starting material samples Review analytical data for compliance to SOPs Assemble and document data for quality review Present and participate in internal and external scientific meetings Revise and update SOPs as needed (e.g., analytical methods, equipment procedures, and material specifications) Conducts analytical investigations Applies knowledge of cGMP and GLP May develop and/or optimize analytical methods May author sections of scientific reports REQUIREMENTS: BS or MS degree in Chemistry or related field 2+ years of experience in analytical development and quality control role Practical knowledge of HPLC, MS, and GC, including operation of instrumentation Familiarity with GMP requirements, with hands-on GMP experience preferred Experience following SOPs and recording data in laboratory notebooks or data collection forms Ability to interpret experimental results and demonstrate good judgement in resolving issues / making recommendations Detail oriented with strong organizational skills Excellent written and verbal communication skills Ability to manage priorities and maintain aggressive timelines for multiple projects Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition #IONIS003987 Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits Full Benefits Link: https://ionis.com/careers#:~:text=Highly%20competitive%20benefits The pay scale for this position is $71,219 to $90,448 NO PHONE CALLS PLEASE. PRINCIPALS ONLY. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Pediatric Neurology Research Unit PROJECT SUMMARY The summer intern position will support the Pediatric Neurology Research Unit at Ionis Pharmaceuticals, reporting to a senior scientist. The intern will lead the phenotypic characterization of a human iPSC-derived induced neuron model of a prevalent neurodevelopmental disorder for which no human disease models exist. The intern will be responsible for developing an action plan in tandem with the supervisor, executing experimental milestones, analyzing data, and presenting results at internal scientific and corporate meetings. BENEFITS OF PROJECT Gain experience and learn about Ionis’ Ways of Working, culture, and cross-functional research environment Hands-on training in culturing and maintaining hiPSC-derived neurons Learn to assess neurodevelopmental phenotypes using core techniques including immunostaining, confocal microscopy, and MEA-based functional analysis Exposure to the biotech drug discovery pipeline and how cellular disease models are used to evaluate therapeutic strategies Develop entrepreneurial and self-driven skills that enhance interpersonal, written, and scientific communication Gain project management skills transferable across scientific, biotech, and business settings Opportunity to strengthen problem-solving skills and adapt to evolving experimental priorities RESPONSIBILITIES Design and execute a project charter and experimental action plan with guidance from the project team Maintain Ngn2-induced iNeurons derived from mutant and control hiPSC lines Perform immunohistochemistry and confocal imaging to assess neuronal differentiation, dendritic morphology, and synaptic density Conduct functional characterization using MEA recordings to evaluate neuronal network activity Analyze and interpret experimental data to identify disease-relevant phenotypes Provide regular project updates and present findings to management and the broader research team QUALIFICATIONS MUST be currently enrolled in a U.S. undergraduate degree program MUST be able to begin the internship between 6/8 and 8/14/2026 MUST be able and willing to remain in the program through at least 8/14/2026 MUST be able and willing to commit to a minimum 40-hour work week MUST be able and willing to work onsite in Carlsbad, CA or remotely, as determined by the team Previous experience with cell culture procedures and basic computer skills preferred Strong interpersonal, written, and verbal communication skills Methodical, organized, and detail-oriented mindset Flexible, adaptable, and able to adjust priorities as project needs evolve Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! GMP Quality and Commercial Supply Chain (EU) SUMMARY The intern will support both Quality Assurance and Supply Chain functions to ensure compliance with cGMP standards and operational efficiency. This role involves assisting with quality system processes, continuous improvement initiatives, and supporting SAP system optimization for commercial supply chain operations. The intern will gain hands-on experience in pharmaceutical quality systems and enterprise resource planning (ERP) tools. This role will be based in the Dublin Office (located in Dublin City Centre) and travel to the US for the internship is part of the role. CORE RESPONSIBILITIES Assist in implementing best practices for Quality processes. Support the performance of Quality systems in compliance with cGMP standards. Participate in continuous improvement initiatives, focusing on efficiency and compliance. Help document and standardize SAP processes, creating a 'Day in the Life' manual for supply chain operations. Review existing SAP process documentation and assist with improvements to meet business needs. Collaborate cross-functionally to ensure accurate process flows and readiness for future changes. Gain knowledge of pharmaceutical legislation, industry best practices, and ERP systems. COMPETENCIES IDENTIFIED FOR SUCCESS Technical aptitude (i.e. able to read and comprehend technical documentation and execute procedures). Excellent communication skills (written and oral). Ability to work cross functionally, focusing on meeting and tracking to schedules and embracing an interdependent work culture. Organization Skills – Ability to manage multiple priorities and know when to escalate issues for resolution. Adaptability and willingness to learn new systems and processes. EDUCATION, EXPERIENCE, AND OTHER REQUIREMENTS Currently pursuing a degree in Science, Engineering, or Information Technology (preferably 3rd year). SAP or similar ERP experience is an advantage. Willingness to travel to the US during the internship. PROGRAM HIGHLIGHTS The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments REQUIREMENTS MUST be currently enrolled in an Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be able and willing to commit to a minimum 40-hour work week. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Cardiovascular and Renal Drug Discovery Summary We are currently seeking a highly motivated summer intern for 2026 to join our Cardiovascular and Renal Drug Discovery team. The intern will contribute to in vitro disease model development and gain hands-on exposure to preclinical drug discovery. This role offers an opportunity to learn how induced pluripotent stem cells (iPSCs) are used to generate cardiovascular disease models with training in advanced molecular and cellular biology techniques. The intern will receive comprehensive training in CRISPR genome editing, including gRNA and HDR template design, monoclonal clone isolation, and validation of genome-edited cell lines using qPCR and dPCR. Additional techniques include RNA and DNA isolation, cell culture, and iPSC clonal expansion. Throughout the internship, the intern will regularly present progress updates and deliver a final presentation to the broader organization. Responsibilities Learn the end-to-end workflow for generating CRISPR-engineered iPSC models of dilated cardiomyopathy (DCM) from isogenic iPSC lines. Establish and characterize monoclonal iPSC lines for DCM disease modeling using CRISPR-based genome editing. Participate in experimental design, data analysis, and scientific discussions within the project team. Prepare and present a formal presentation at the conclusion of the internship. Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Requirements: MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship MUST be able to begin internship between 06/08/25 and 08/14/26 MUST be able and willing to remain in the program through at least 08/14/26 MUST be able and willing to commit to a minimum 40-hour workweek MUST be able and willing to work onsite at Carlsbad, CA Hands-on laboratory experience is a plus but not required Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! New Product Strategy (Neurology) Summary Support the hiring manager and cross-functional stakeholders in a strategic deep dive on the 10-year outlook for alpha synucleinopathies (e.g., Parkinson’s disease [PD], Parkinson’s disease dementia [PDD], Dementia with Lewy Bodies [DLB], Multiple System Atrophy [MSA]). This internship will partner closely with internal teams and a consulting vendor to synthesize the evolving disease area, future market and competitive landscape, and the key drivers shaping diagnostics, biomarkers, and emerging disease-modifying modalities (e.g., small molecules, biologics, antisense oligonucleotides, gene therapies, immunotherapies). This position will work across multiple indications and stakeholders and will support a consolidated view of epidemiology, care pathways, competitive dynamics, access/pricing trends, and innovation risk/benefit to inform clear where-to-play/how-to-win options. Showcase your work with a final presentation (PPT) near the conclusion of your internship. What You’ll Do Support a 10-year strategic deep dive across MSA, PD, PDD, and DLB to map market size, segments, access dynamics, and the evolving competitive landscape Conduct structured literature and secondary data synthesis to consolidate the current and future state of the disease area (diagnostics, biomarkers, care pathways, treatment paradigms) Perform pipeline and clinical benchmarking, including key catalysts, readouts, and inflection points across modalities Contribute to building and/or refining market models with segmentation, sensitivities, and assumptions to estimate future scenarios and unmet need Support market research team, including guide/questionnaire development and insight generation review (e.g., HCP perspectives) in collaboration with internal stakeholders and vendor partners Work with cross-functional team and consultant to develop 2–3 scenario plans to pressure-test strategic options Synthesize findings into a reusable strategy package: disease/market maps, quantified unmet needs, prioritized recommendations. Expected Outcomes / Deliverables Disease & market maps for PD/PDD/DLB/MSA with key inflection points and catalysts over a 10-year horizon A current competitive landscape and catalyst view, with implications for strategy and portfolio choices Prioritized recommendations: where-to-play/how-to-win An executive readout deck (PPT) presented at the end of the internship What You’ll Gain Deep domain fluency in alpha synucleinopathies and emerging disease-modifying approaches A practical strategy toolkit (sizing, segmentation, benchmarking, scenario modeling) Experience translating complex inputs into executive-ready storytelling High-visibility exposure through collaboration with cross-functional leaders and external partners Required Qualifications Must be at least 18 years old Must have a minimum GPA of 2.8 Authorized to work in the United States without sponsorship now or in the future, or eligible through CPT/OPT via your university Must be currently enrolled as a full-time student in a Master’s/MBA/PhD/PharmD (or similar graduate/doctoral program) at an accredited US-based university or college Must be a Graduate or Doctoral Student Must be enrolled full-time in the Fall semester at an accredited university/college after the completion of the internship Must be able to complete a 10–12 consecutive week internship between June and September Preferred Qualifications Preferred degree qualification: Graduate/MBA/PhD/PharmD (or related) Proficiency with MS Office Suite (Excel and PowerPoint in particular) Familiarity with life sciences/biopharma strategy, market research, or healthcare analytics (coursework or experience) Strong analytical and structured problem-solving skills (market sizing, segmentation, scenario thinking) Ability to identify issues, seek solutions, and operate effectively in ambiguity Ability to work both independently and collaboratively with cross-functional teams and external partners Clear written and verbal communication skills; comfort synthesizing into executive-ready storylines Efficient, organized, and able to handle short timelines in a fast-paced environment Demonstrated commitment to inclusion and diversity in the workplace Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Requirements: MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be able and willing to commit to a minimum 40-hour work week. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Medicinal Chemistry Summary: The project will involve multi-step organic synthesis. While working on the target molecules, the student intern will gain hands-on experience in multi-step synthetic techniques and modern spectroscopic methods. Additionally, the intern will be immersed in the scientific environment at Ionis, reinforcing their interest in science—one of the key goals of our internship program. Qualifications: Currently enrolled as a Chemistry major with experience in organic chemistry laboratory work Knowledge of organic chemistry lab safety practices preferred Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Requirements: MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be able and willing to commit to a minimum 40-hour work week. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Lead Identification – NGS group SUMMARY: We are seeking an enthusiastic and highly motivated undergraduate student who is currently enrolled in a molecular or cellular biology-based program to join the Lead Identification – NGS group as a 2026 summer intern. The intern will work within a fast-paced, highly productive, and collaborative research environment and have the opportunity to make impactful contributions to Ionis’ RNA sequencing (RNAseq) workflow in support of drug discovery. This internship project will focus on implementing and optimizing a new RNAseq assay. The intern will gain hands-on experience with library preparation, lab liquid handlers, and next-generation sequencing. The goal of the project is to compare our current workflow to a new, multiplexed workflow to increase throughput of RNAseq samples while maintaining high data quality. RESPONSIBILITIES: Learn and perform the current RNAseq library preparation protocol to establish a quality benchmark Assist in optimizing the multiplexed RNAseq protocol to increase assay throughput Support and learn to write protocols on liquid handlers Assist with optimization of automation conditions Learn to QC RNAseq libraries Load sequencers and understand basic QC metrics Collaborate with scientists across NGS and automation teams to refine workflows Present project results at the end of the internship program. REQUIREMENTS: Must be enrolled in an undergraduate molecular biology, cell biology or other related program Must have completed one quarter/semester of biology or chemistry lab-based coursework Must be able to commit to full 10 week program Must be able to commit to 40 hour work week and work onsite in Carlsbad, CA MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. PROGRAM HIGHLIGHTS: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Pulmonary Drug Discovery Role overview: Support a preclinical project to compare two RNA-therapeutic strategies for non-cystic fibrosis bronchiectasis using an established mouse model and standard molecular/phenotypic endpoints to help determine the optimal therapeutic approach. Responsibilities (under supervision/training): Execute and help optimize an NCFB-like mouse model protocol (building on published/internal methods) and ensure proper controls and documentation Support in vivo study activities (rodent handling, dosing, tissue collection) following SOPs and animal welfare requirements Process samples (tissue homogenization, RNA extraction) and quantify key markers of inflammation and muco-obstruction using qPCR, ELISA or related assays Organize/analyze data and communicate results via weekly updates and a final summary/presentation Success criteria by end of internship: a reproducible model protocol + a comparative dataset and recommendation on strategy. Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Requirements: MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be able and willing to commit to a minimum 40-hour work week. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Corporate Operations (Launch Readiness) Summary The Corporate Operations team takes on complex enterprise initiatives to drive organizational performance and outcomes. As a member of this team, you will support Ionis’s cross-functional launch readiness efforts for upcoming product launches, including TRYNGOLZA for sHTG and zilganersen for Alexander’s Disease. The Corporate Operations Summer Intern will contribute to key launch readiness activities spanning pre-launch planning to post-launch support. Working across enabling functions such as Accounting, Finance, HR, IT, Quality, Safety/PV, and Legal, they will help coordinate key activities, track milestones, and identify potential risks to ensure alignment across teams. This experience will provide the intern with exposure to how diverse teams prepare for commercialization and what it takes to bring a product to market. The intern will build skills in leadership, strategic project management, and cross-functional collaboration while contributing to Ionis’s overall launch readiness success. Responsibilities Own the preparation and follow-through for cross-functional launch readiness meetings, including shaping agendas, synthesizing discussions, and tracking decisions and commitments Manage launch readiness trackers and status dashboards, ensuring accuracy and providing visibility into progress across enabling functions in support of Commercial readiness Identify risks, gaps, and dependencies and proactively communicate findings to support informed decision-making and mitigation strategies Prepare executive-level presentations for Commercial and leadership that consolidate updates from enabling teams (e.g., Finance, HR, IT, Quality, Safety/PV, Legal) Contribute to ad hoc project work that supports alignment between enabling functions and Commercial teams throughout pre-launch and post-launch activities Requirements Currently pursuing a bachelor’s or master’s degree in business, life sciences, public health, engineering or a related field Strong organizational and time management skills, with the ability to support multiple workstreams simultaneously Clear and effective written and verbal communication skills Ability to work collaboratively with diverse teams and stakeholders Comfortable working in a dynamic environment with shifting priorities and timelines Interested in learning about pharmaceutical commercialization, launch readiness, and cross-functional operations in a collaborative environment Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Requirements: MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be able and willing to commit to a minimum 40-hour work week. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Antibody Engineering Role Overview The summer intern will work on a cutting-edge ligand engineering project focused on optimizing Blood-Brain Barrier (BBB) ligands for the delivery of oligonucleotides. This involves applying protein engineering techniques and leveraging yeast surface display technology to identify novel clones with improved central nervous system (CNS) delivery of oligonucleotide payloads. Key Responsibilities Protein Engineering: Perform high-throughput mutational scanning on BBB ligands to improve the delivery of oligonucleotides to the CNS. Yeast Culture Operation, Molecular Biology, and Surface Display: Implement and utilize yeast display platforms to present engineered variants for screening. Conjugation Analysis: Conjugate variants to oligonucleotides and assess conjugation efficiency. Functional Evaluation: Use multi-parameter flow cytometry to evaluate expression levels, antigen-binding functionality, and conjugation success. Data Interpretation: Analyze experimental results to identify mutants with improved CNS delivery. Learning & Development Opportunities Hands-on experience in molecular biology, protein biochemistry, and flow cytometry. Exposure to advanced antibody engineering strategies and ligand design. Opportunity to contribute to a project with potential for publication and real-world impact. Expectations Strong interest in biotechnology, molecular biology, or related fields. Ability to work independently and collaboratively in a research environment. Attention to detail and willingness to learn new techniques. Commitment to scientific rigor and problem-solving. Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite interns only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Requirements: MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be able and willing to commit to a minimum 40-hour work week. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career! Pharmaceutical Development Summary: Ionis is offering a Summer Internship within our Pharmaceutical Development team for a motivated student interested in drug formulation, chemistry, and data driven research. This role provides hands on experience supporting the development of oligonucleotide-based medicines, including antisense oligonucleotides and siRNA therapeutics. The intern will work closely with an experienced scientist mentor on a research project focused on understanding how formulation components such as drug chemistry, pH, and buffering systems affect drug product performance. This internship is designed to help students connect classroom learning to real world pharmaceutical development while building strong technical and professional skills. What You Will Do Conduct laboratory experiments to evaluate formulation properties such as pH and buffer capacity Assist with experimental planning, sample preparation, and data collection Analyze and interpret experimental data using basic modeling and data analysis tools Learn how formulation decisions impact drug stability, quality, and patient experience Prepare summaries and presentations to share findings with the project team Collaborate with scientists across Pharmaceutical Development and related functions What You Will Learn Fundamentals of pharmaceutical formulation and drug product development How chemistry and molecular properties influence drug stability and performance Practical experience with experimental design, data analysis, and scientific communication Exposure to the research and development environment within a biotech company Professional skills through mentorship, teamwork, and presentations Who Should Apply Required Qualifications: Currently enrolled in a bachelors, masters, or doctoral program in Chemistry, Pharmaceutical Sciences, Chemical Engineering, Biochemistry, or a related field Completion of general and organic chemistry coursework or equivalent Strong interest in pharmaceutical or biotech research Ability to work independently and collaboratively in a laboratory setting Preferred Qualifications: Coursework or experience in organic chemistry, analytical chemistry, or pharmaceutics Familiarity with pH, buffers, or acid base chemistry Experience with data analysis tools such as Excel, JMP, Graphpad Prism Curiosity, attention to detail, and enthusiasm for learning Program Highlights: The program is designed to complement a student’s undergraduate and/or graduate studies with relevant, hands-on industry experience Ionis offers paid positions Weekly stipend (for onsite students only) Professional Networking End-of-program project presentations Housing/Travel assistance available for eligible, out-of-area interns Networking and bonding social events Interaction with diverse and motivated teams/departments Requirements: MUST be currently enrolled in a U.S. Undergraduate and/or Graduate Degree Program and not graduating prior to the completion of the Ionis internship. MUST be able to begin internship between 6/8 and 8/14/2026. MUST be able and willing to remain in program through at least 8/14/2026. MUST be able and willing to commit to a minimum 40-hour work week. Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position The pay scale for this position is $18 to $23 per hour. NO PHONE CALLS PLEASE. PRINCIPALS ONLY. APPLICATION DEADLINE IS April 30, 2026. PLEASE INCLUDE A COVER LETTER RELEVANT TO THE POSITION APPLYING FOR. THE EVALUATION PROCESS MAY COMMENCE PRIOR TO THIS DEADLINE. Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.